By , (Reuters) - Wall Street is moving some bets on COVID-19 vaccines to large pharmaceutical companies with robust manufacturing capabilities, signaling that a love affair with small biotech firms might be ending after the sector’s best quarter in almost 20 years.Some of the selling was likely driven by end-of-quarter profit-taking, locking in dizzying gains in an otherwise turbulent market. Moderna and Inovio shares have risen nearly 200 percent and 540 percent in the year-to-date, respectively, greatly eclipsing gains for large pharmaceutical companies.Analysts say investors are changing...…By , (Reuters) - Wall Street is moving some bets on COVID-19 vaccines to large pharmaceutical companies with robust manufacturing capabilities, signaling that a love affair with small biotech firms might be ending after the sector’s best quarter in almost 20 years.Some of the selling was likely driven by end-of-quarter profit-taking, locking in dizzying gains in an otherwise turbulent market. Moderna and Inovio shares have risen nearly 200 percent and 540 percent in the year-to-date, respectively, greatly eclipsing gains for large pharmaceutical companies.Analysts say investors are changing...WW…

Register now for FREE unlimited access to Reuters.comLONDON, April 9 (Reuters) - Investors have pumped more money into equities over the past five months than in the last 12 years, BofA's weekly flow figures showed on Friday, as ultra-easy monetary policies and unprecedented stimulus has sparked a secular shift into stocks.BofA said $576 billion had gone into equity funds in the past five months, beating the combined $452 billion inflows seen in the last 12 years,Based on clients' asset allocations, Bofa said a record 63.6% of the money was invested in stocks, 18.5% in debt and 11.6% in...…Register now for FREE unlimited access to Reuters.comLONDON, April 9 (Reuters) - Investors have pumped more money into equities over the past five months than in the last 12 years, BofA's weekly flow figures showed on Friday, as ultra-easy monetary policies and unprecedented stimulus has sparked a secular shift into stocks.BofA said $576 billion had gone into equity funds in the past five months, beating the combined $452 billion inflows seen in the last 12 years,Based on clients' asset allocations, Bofa said a record 63.6% of the money was invested in stocks, 18.5% in debt and 11.6% in...WW…

By LONDON (Reuters) - The U.S. Treasury is due to run down a $1.6 trillion bank account at the Federal Reserve as government spending ramps up in the months ahead - a move some analysts warn may crush short-term money rates further and flood financial markets with cash.The Treasury said recently it would halve its extraordinarily large balance at the so-called Treasury General Account (TGA) by April and cut it to $500 billion by the end of June.Graphic: Treasury cash balance -Here’s what’s involved and its potential fallout:The U.S. government runs most of its day-to-day business through...…By LONDON (Reuters) - The U.S. Treasury is due to run down a $1.6 trillion bank account at the Federal Reserve as government spending ramps up in the months ahead - a move some analysts warn may crush short-term money rates further and flood financial markets with cash.The Treasury said recently it would halve its extraordinarily large balance at the so-called Treasury General Account (TGA) by April and cut it to $500 billion by the end of June.Graphic: Treasury cash balance -Here’s what’s involved and its potential fallout:The U.S. government runs most of its day-to-day business through...WW…

By , BOSTON/LONDON (Reuters) - Wall Street is gearing up for another week of market mayhem, with signs that the retail frenzy that pumped up the stock prices of the likes of GameStop Corp and AMC Entertainment Holdings Inc is spreading to other assets.Slideshow Some of Wall Street’s largest hedge funds are still licking their wounds after retail traders sought to drive up the prices of stocks that were heavily bet against, resulting in large losses for major investors.Melvin Capital, a hedge fund at the center of the GameStop drama, lost 53% in January but received commitments for fresh...…By , BOSTON/LONDON (Reuters) - Wall Street is gearing up for another week of market mayhem, with signs that the retail frenzy that pumped up the stock prices of the likes of GameStop Corp and AMC Entertainment Holdings Inc is spreading to other assets.Slideshow Some of Wall Street’s largest hedge funds are still licking their wounds after retail traders sought to drive up the prices of stocks that were heavily bet against, resulting in large losses for major investors.Melvin Capital, a hedge fund at the center of the GameStop drama, lost 53% in January but received commitments for fresh...WW…

By , BOSTON/LONDON (Reuters) - Wall Street is gearing up for another week of market mayhem, with signs that the retail frenzy that pumped up the stock prices of the likes of GameStop Corp and AMC Entertainment Holdings Inc is spreading to other assets.Slideshow Some of Wall Street’s largest hedge funds are still licking their wounds after retail traders sought to drive up the prices of stocks that were heavily bet against, resulting in large losses for major investors.Melvin Capital, a hedge fund at the center of the GameStop drama, lost 53% in January but received commitments for fresh...…By , BOSTON/LONDON (Reuters) - Wall Street is gearing up for another week of market mayhem, with signs that the retail frenzy that pumped up the stock prices of the likes of GameStop Corp and AMC Entertainment Holdings Inc is spreading to other assets.Slideshow Some of Wall Street’s largest hedge funds are still licking their wounds after retail traders sought to drive up the prices of stocks that were heavily bet against, resulting in large losses for major investors.Melvin Capital, a hedge fund at the center of the GameStop drama, lost 53% in January but received commitments for fresh...WW…

By LONDON (Reuters) - Short-sellers are sitting on estimated losses of $70.87 billion from their short positions in U.S. companies so far this year, data from financial data analytics firm Ortex showed on Thursday.The hefty losses come as shares of highly-shorted GameStop jumped more than 1,000% in the past week without a clear business reason, forcing short-sellers to buy back into the stock to cover potential losses -- defined as a short-squeeze -- while retail investors then piled in to benefit from the surge.Chasing shorted companies became a trend among retail traders, rippling across...…By LONDON (Reuters) - Short-sellers are sitting on estimated losses of $70.87 billion from their short positions in U.S. companies so far this year, data from financial data analytics firm Ortex showed on Thursday.The hefty losses come as shares of highly-shorted GameStop jumped more than 1,000% in the past week without a clear business reason, forcing short-sellers to buy back into the stock to cover potential losses -- defined as a short-squeeze -- while retail investors then piled in to benefit from the surge.Chasing shorted companies became a trend among retail traders, rippling across...WW…