Stanford University School of Medicine
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Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring

Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring

You are currently viewing the abstract.AAAS login provides access to Science for AAAS members, and access to other journals in the Science family to users who have purchased individual subscriptions.Log in via OpenAthens.Log in with your institution via Shibboleth.Download and print this article for your personal scholarly, research, and educational use.Buy a single issue of Science for just $15 USD.Wounds in adult mammals typically heal by forming fibrotic scars. Mascharak et al. found that a specific population of skin fibroblasts (Engrailed-1 lineage–negative fibroblasts) activate...

April 23, 2021
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Influence of a COVID-19 vaccine’s effectiveness and safety profile on vaccination acceptance

Influence of a COVID-19 vaccine’s effectiveness and safety profile on vaccination acceptance

Edited by Douglas S. Massey, Princeton University, Princeton, NJ, and approved January 21, 2021 (received for review October 16, 2020)Acceptance of vaccines has been on the decline in recent years. Despite encouraging early results for coronavirus vaccine trials, achieving herd immunity requires substantial uptake. We presented scenarios varying vaccine efficacy, minor side effects, and severe reactions to a sample representative of the US population. Vaccine acceptance improved when the efficacy increased beyond 70%. Respondents were unaffected by the probability of minor side effects,...

March 9, 2021
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