Queen Mary University of London
Queen Mary University of London
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Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

You are currently viewing the abstract.AAAS login provides access to Science for AAAS members, and access to other journals in the Science family to users who have purchased individual subscriptions.Log in via OpenAthens.Log in with your institution via Shibboleth.Download and print this article for your personal scholarly, research, and educational use.Buy a single issue of Science for just $15 USD.B cells undergo affinity maturation and class switch recombination (CSR) within germinal centers (GCs) to facilitate protective antibody responses against pathogens. King et al. performed...

February 12, 2021
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Speed of sound from fundamental physical constants

Speed of sound from fundamental physical constants

Two dimensionless fundamental physical constants, the fine structure constant α and the proton-to-electron mass ratio , are attributed a particular importance from the point of view of nuclear synthesis, formation of heavy elements, planets, and life-supporting structures. Here, we show that a combination of these two constants results in a new dimensionless constant that provides the upper bound for the speed of sound in condensed phases, vu. We find that , where c is the speed of light in vacuum. We support this result by a large set of experimental data and first-principles computations...

October 1, 2020
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