Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.AdvertisementRisky ‘gain-of-function’ studies need stricter guidance, say US researchersYou have full access to this article via your institution.Researchers and biosecurity specialists are calling on the US government to issue clearer guidance about experiments it...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.AdvertisementRisky ‘gain-of-function’ studies need stricter guidance, say US researchersYou have full access to this article via your institution.Researchers and biosecurity specialists are calling on the US government to issue clearer guidance about experiments it...WW…

ABOVE: A mouse’s crushed optic nerve, composed of retinal ganglion cell axons (bright streaks), regenerates after researchers injected a virus into the eye that contains genes whose activity dedifferentiates cells into a more youthful state, allowing them to regrow.oss of visual acuity is a common feature of aging, whether it’s from age-related conditions such as glaucoma, an impaired ability for cells to respond to damage, or degeneration. In an attempt to address these issues with a genetic intervention, scientists reprogrammed neurons in mouse eyes to regrow after inducing glaucoma or...…ABOVE: A mouse’s crushed optic nerve, composed of retinal ganglion cell axons (bright streaks), regenerates after researchers injected a virus into the eye that contains genes whose activity dedifferentiates cells into a more youthful state, allowing them to regrow.oss of visual acuity is a common feature of aging, whether it’s from age-related conditions such as glaucoma, an impaired ability for cells to respond to damage, or degeneration. In an attempt to address these issues with a genetic intervention, scientists reprogrammed neurons in mouse eyes to regrow after inducing glaucoma or...WW…

cientists are testing if COVID-19 vaccines will protect against newly identified UK and South African SARS-CoV-2 variants, both of which contain an unusual number of mutations compared to other variants of the coronavirus. These mutations are concentrated mainly in the segment of the virus’s genome that codes for the spike protein, which the Pfizer/BioNTech, Moderna, and Oxford-AstraZeneca vaccines each build immunity to.“One of the reasons they know they’ve got a problem is because, like us, they have an excellent genomic scientific capability to be able to study the details of the virus,”...…cientists are testing if COVID-19 vaccines will protect against newly identified UK and South African SARS-CoV-2 variants, both of which contain an unusual number of mutations compared to other variants of the coronavirus. These mutations are concentrated mainly in the segment of the virus’s genome that codes for the spike protein, which the Pfizer/BioNTech, Moderna, and Oxford-AstraZeneca vaccines each build immunity to.“One of the reasons they know they’ve got a problem is because, like us, they have an excellent genomic scientific capability to be able to study the details of the virus,”...WW…