Gerardo G Herrera
Gerardo G Herrera
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Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds

Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds

Share this articleDoiCopy to clipboardCite this articleLef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundseLife 9:e60066.Copy to clipboardScars are a serious health concern for burn victims and individuals with skin conditions associated with wound healing. Here, we identify regenerative factors in neonatal murine skin that transforms adult skin to regenerate instead of only repairing wounds with a scar, without perturbing development and homeostasis. Using scRNA-seq to probe unsorted cells from regenerating, scarring, homeostatic, and...

September 29, 2020
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