This article was published more than 2 years agoCommentGift ShareIn 2010, John Mandrola was 46 years old and training like a demon for the USA Cycling Masters Road National Championships when, out on a ride, his heart started beating erratically. He diagnosed it immediately, because, in addition to being an accomplished endurance athlete, Mandrola is also a cardiac electrophysiologist. What he was experiencing was a condition he treats every day at work: atrial fibrillation, or AFib, a heart-rhythm disturbance that can feel like you can’t catch your breath or get your heart rate under...…This article was published more than 2 years agoCommentGift ShareIn 2010, John Mandrola was 46 years old and training like a demon for the USA Cycling Masters Road National Championships when, out on a ride, his heart started beating erratically. He diagnosed it immediately, because, in addition to being an accomplished endurance athlete, Mandrola is also a cardiac electrophysiologist. What he was experiencing was a condition he treats every day at work: atrial fibrillation, or AFib, a heart-rhythm disturbance that can feel like you can’t catch your breath or get your heart rate under...WW…

This article was published more than 2 years agoCommentGift ShareThis article is free to access.Why?The Washington Post is providing this news free to all readers as a public service.Follow this story and more by With the Fourth of July just around the corner and many states and communities , the warm sunny weather beckons. But infectious-disease experts warn that the virus remains a threat as we return to travel, swimming, barbecues, ice cream shops and restaurants.So what do we need to know about the new coronavirus and covid-19, the disease it causes, that is important as we embark...…This article was published more than 2 years agoCommentGift ShareThis article is free to access.Why?The Washington Post is providing this news free to all readers as a public service.Follow this story and more by With the Fourth of July just around the corner and many states and communities , the warm sunny weather beckons. But infectious-disease experts warn that the virus remains a threat as we return to travel, swimming, barbecues, ice cream shops and restaurants.So what do we need to know about the new coronavirus and covid-19, the disease it causes, that is important as we embark...WW…

This article was published more than 2 years agoCommentGift ShareIn February, pharmaceutical companies Roche and Eli Lilly that two experimental drugs they had developed for Alzheimer’s disease had failed in clinical trials. Roche’s drug, gantenerumab, and Eli Lilly’s solanezumab joined more than 100 other potential Alzheimer’s drugs that have flopped, including aducanumab, a much-heralded drug from Biogen.In March 2019, Biogen of the drug early after an interim analysis showed they weren’t working, but the company , saying it intends to seek approval from the Food and Drug...…This article was published more than 2 years agoCommentGift ShareIn February, pharmaceutical companies Roche and Eli Lilly that two experimental drugs they had developed for Alzheimer’s disease had failed in clinical trials. Roche’s drug, gantenerumab, and Eli Lilly’s solanezumab joined more than 100 other potential Alzheimer’s drugs that have flopped, including aducanumab, a much-heralded drug from Biogen.In March 2019, Biogen of the drug early after an interim analysis showed they weren’t working, but the company , saying it intends to seek approval from the Food and Drug...WW…

On New Year’s Eve 2017, sheriff’s deputies in the Denver suburb of Highlands Ranch responded to a domestic disturbance. Before the night was over, four officers had been shot and Douglas County Sheriff’s Deputy Zackari Parrish III was dead.This story also ran on . It can beThe gunman was a 37-year-old man with a whose family had previously tried to take his guns away but found themselves without legal recourse to do so.“We tried every legal avenue we could to not only protect him, but to protect the community,” said Douglas County Sheriff Tony Spurlock. At that time, however, there was...…On New Year’s Eve 2017, sheriff’s deputies in the Denver suburb of Highlands Ranch responded to a domestic disturbance. Before the night was over, four officers had been shot and Douglas County Sheriff’s Deputy Zackari Parrish III was dead.This story also ran on . It can beThe gunman was a 37-year-old man with a whose family had previously tried to take his guns away but found themselves without legal recourse to do so.“We tried every legal avenue we could to not only protect him, but to protect the community,” said Douglas County Sheriff Tony Spurlock. At that time, however, there was...WW…

This article was published more than 2 years agoCommentGift ShareDuring the long, cold days of winter, it’s easy to fall off even the most well-intentioned exercise program. After months of travel and stay-at-home restrictions, exercising in the confined spaces of home isn’t exactly enticing, but frigid weather, along with fewer hours of daylight and, in some cases, snow, can make it hard to leave the cozy comfort of the indoors to exercise outside.Don’t be deterred — winter can be a great time for outdoor activities, says Keri Denay, a family and sports physician at the University of...…This article was published more than 2 years agoCommentGift ShareDuring the long, cold days of winter, it’s easy to fall off even the most well-intentioned exercise program. After months of travel and stay-at-home restrictions, exercising in the confined spaces of home isn’t exactly enticing, but frigid weather, along with fewer hours of daylight and, in some cases, snow, can make it hard to leave the cozy comfort of the indoors to exercise outside.Don’t be deterred — winter can be a great time for outdoor activities, says Keri Denay, a family and sports physician at the University of...WW…

This story also ran on . It can beGRAND JUNCTION, Colo. — On a sunny Saturday in January, Ruth Hatfield was sitting with a friend’s dog on a sidewalk bench in downtown Grand Junction. Back home in Snowmass Village, 120 miles away through winding Rocky Mountain roadways, local officials had just shut down indoor restaurant dining as covid cases reached some of the highest levels in Colorado.Here in Grand Junction, though, restaurants were open, and Hatfield had sought out those with the local health department’s “5-star certifications,” a designation meant to reassure people it is safe to...…This story also ran on . It can beGRAND JUNCTION, Colo. — On a sunny Saturday in January, Ruth Hatfield was sitting with a friend’s dog on a sidewalk bench in downtown Grand Junction. Back home in Snowmass Village, 120 miles away through winding Rocky Mountain roadways, local officials had just shut down indoor restaurant dining as covid cases reached some of the highest levels in Colorado.Here in Grand Junction, though, restaurants were open, and Hatfield had sought out those with the local health department’s “5-star certifications,” a designation meant to reassure people it is safe to...WW…

entry , been discussed on , scored a from Cards Against Humanity, and now it’s been featured in on the TV game show Jeopardy. Metascience nerds rejoice! The term p-hacking has gone mainstream.Results from a study can be analyzed in a variety of ways, and p-hacking refers to a practice where researchers select the analysis that yields a pleasing result. The p refers to the p-value, a statistical entity that’s essentially a measure of how surprising the results of a study would be if the effect you’re looking for wasn’t there.Suppose you’re testing a pill for high blood pressure, and you find...…entry , been discussed on , scored a from Cards Against Humanity, and now it’s been featured in on the TV game show Jeopardy. Metascience nerds rejoice! The term p-hacking has gone mainstream.Results from a study can be analyzed in a variety of ways, and p-hacking refers to a practice where researchers select the analysis that yields a pleasing result. The p refers to the p-value, a statistical entity that’s essentially a measure of how surprising the results of a study would be if the effect you’re looking for wasn’t there.Suppose you’re testing a pill for high blood pressure, and you find...WW…

This story also ran on .TELLURIDE, Colo. — The day after Thanksgiving, Dr. Jana Eller and Dr. Shiraz Naqvi were seated beside an outdoor fire pit at the base of Telluride Ski Resort, taking a short break from skiing.The two physicians from Houston had driven more than 18 hours to get here for the holiday weekend, and they were staying (and preparing meals) in a home. They traveled with another couple and their kids, colleagues they’ve been “bubbling” with in Houston.“We got a COVID test prior to leaving and will get another when we return,” Naqvi said.The skiing itself doesn’t feel much...…This story also ran on .TELLURIDE, Colo. — The day after Thanksgiving, Dr. Jana Eller and Dr. Shiraz Naqvi were seated beside an outdoor fire pit at the base of Telluride Ski Resort, taking a short break from skiing.The two physicians from Houston had driven more than 18 hours to get here for the holiday weekend, and they were staying (and preparing meals) in a home. They traveled with another couple and their kids, colleagues they’ve been “bubbling” with in Houston.“We got a COVID test prior to leaving and will get another when we return,” Naqvi said.The skiing itself doesn’t feel much...WW…

In May, the Brazilian city of Manaus was devastated by a large outbreak of COVID-19. Hospitals were overwhelmed and the city was digging new grave sites in the surrounding forest. But by August, something had shifted. Despite relaxing social-distancing requirements in early June, the city of 2 million people had reduced its number of excess deaths from around 120 per day to nearly zero.In September, two groups of researchers posted preprints suggesting that Manaus’s late-summer slowdown in COVID-19 cases had happened, at least in part, because a large proportion of the community’s...…In May, the Brazilian city of Manaus was devastated by a large outbreak of COVID-19. Hospitals were overwhelmed and the city was digging new grave sites in the surrounding forest. But by August, something had shifted. Despite relaxing social-distancing requirements in early June, the city of 2 million people had reduced its number of excess deaths from around 120 per day to nearly zero.In September, two groups of researchers posted preprints suggesting that Manaus’s late-summer slowdown in COVID-19 cases had happened, at least in part, because a large proportion of the community’s...WW…

*Editor's Note (1/3/21): The number of COVID deaths in the U.S. is now more than 350,000, as of the beginning of January, according to the . A persistent falsehood has been circulating on social media: the number of COVID deaths is much lower than official statistics, and therefore the danger of the disease has been overblown. In August, President Donald Trump retweeted a post claiming that only 6 percent of these reported deaths were actually from COVID-19. (The tweet originated from a follower of the debunked conspiracy fantasy QAnon.) Twitter removed the post for...…*Editor's Note (1/3/21): The number of COVID deaths in the U.S. is now more than 350,000, as of the beginning of January, according to the . A persistent falsehood has been circulating on social media: the number of COVID deaths is much lower than official statistics, and therefore the danger of the disease has been overblown. In August, President Donald Trump retweeted a post claiming that only 6 percent of these reported deaths were actually from COVID-19. (The tweet originated from a follower of the debunked conspiracy fantasy QAnon.) Twitter removed the post for...WW…