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High genetic contribution to anterior cruciate ligament rupture: Heritability ~69%

High genetic contribution to anterior cruciate ligament rupture: Heritability ~69%

Article TextOriginal researchHigh genetic contribution to anterior cruciate ligament rupture: Heritability ~69%Objectives We aimed to determine the lifetime genetic risk for anterior cruciate ligament (ACL) rupture.Methods We used a twin study approach, linking the Swedish Twin Register with national healthcare data to form a 30 year, population wide, longitudinal twin cohort. We studied ACL rupture in this cohort of 88 414 identical and fraternal twins, aged ≥17 years, to determine the familial risk and heritability of ACL rupture.Results The incidence rate of ACL rupture was 70 (95% CI 66...

November 10, 2020
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bmj.com

bmj.com

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