Edited by Boris I. Shraiman, University of California, Santa Barbara, CA, and approved January 29, 2021 (received for review September 19, 2020)Fluid flow plays an important role during oogenesis. From insects to mice, oocytes mature by acquiring cytoplasm from sister germ cells, yet the biological and physical mechanisms underlying this transport process remain poorly understood. To study the dynamics of “nurse cell dumping” in fruit flies, we combined direct imaging with flow-network modeling and found that the intercellular pattern and time scale of transport are in accordance with a...…Edited by Boris I. Shraiman, University of California, Santa Barbara, CA, and approved January 29, 2021 (received for review September 19, 2020)Fluid flow plays an important role during oogenesis. From insects to mice, oocytes mature by acquiring cytoplasm from sister germ cells, yet the biological and physical mechanisms underlying this transport process remain poorly understood. To study the dynamics of “nurse cell dumping” in fruit flies, we combined direct imaging with flow-network modeling and found that the intercellular pattern and time scale of transport are in accordance with a...WW…