Share this articleDoiCopy to clipboardCite this articleEvolution of the complex transcription network controlling biofilm formation in Candida specieseLife 10:e64682.Copy to clipboardWe examine how a complex transcription network composed of seven ‘master’ regulators and hundreds of target genes evolved over a span of approximately 70 million years. The network controls biofilm formation in several Candida species, a group of fungi that are present in humans both as constituents of the microbiota and as opportunistic pathogens. Using a variety of approaches, we observed two major types of...…Share this articleDoiCopy to clipboardCite this articleEvolution of the complex transcription network controlling biofilm formation in Candida specieseLife 10:e64682.Copy to clipboardWe examine how a complex transcription network composed of seven ‘master’ regulators and hundreds of target genes evolved over a span of approximately 70 million years. The network controls biofilm formation in several Candida species, a group of fungi that are present in humans both as constituents of the microbiota and as opportunistic pathogens. Using a variety of approaches, we observed two major types of...WW…