Share this articleDoiCopy to clipboardCite this articleIntegron activity accelerates the evolution of antibiotic resistanceeLife 10:e62474.Copy to clipboardMobile integrons are widespread genetic platforms that allow bacteria to modulate the expression of antibiotic resistance cassettes by shuffling their position from a common promoter. Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique recombination and expression system is thought to allow bacteria to ‘evolve on demand’ in response to antibiotic pressure. To test this...…Share this articleDoiCopy to clipboardCite this articleIntegron activity accelerates the evolution of antibiotic resistanceeLife 10:e62474.Copy to clipboardMobile integrons are widespread genetic platforms that allow bacteria to modulate the expression of antibiotic resistance cassettes by shuffling their position from a common promoter. Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique recombination and expression system is thought to allow bacteria to ‘evolve on demand’ in response to antibiotic pressure. To test this...WW…