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Evolution of the complex transcription network controlling biofilm formation in Candida species

Evolution of the complex transcription network controlling biofilm formation in Candida species

Share this articleDoiCopy to clipboardCite this articleEvolution of the complex transcription network controlling biofilm formation in Candida specieseLife 10:e64682.Copy to clipboardWe examine how a complex transcription network composed of seven ‘master’ regulators and hundreds of target genes evolved over a span of approximately 70 million years. The network controls biofilm formation in several Candida species, a group of fungi that are present in humans both as constituents of the microbiota and as opportunistic pathogens. Using a variety of approaches, we observed two major types of...

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