Avshalom Caspi
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Share this articleDoiCopy to clipboardCite this articleQuantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithmeLife 9:e54870.Copy to clipboardBiological aging is the gradual, progressive decline in system integrity that occurs with advancing chronological age, causing morbidity and disability. Measurements of the pace of aging are needed as surrogate endpoints in trials of therapies designed to prevent disease by slowing biological aging. We report a blood-DNA-methylation measure that is sensitive to variation in pace of...…Share this articleDoiCopy to clipboardCite this articleQuantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithmeLife 9:e54870.Copy to clipboardBiological aging is the gradual, progressive decline in system integrity that occurs with advancing chronological age, causing morbidity and disability. Measurements of the pace of aging are needed as surrogate endpoints in trials of therapies designed to prevent disease by slowing biological aging. We report a blood-DNA-methylation measure that is sensitive to variation in pace of...WW…