Name: Persistent metabolic youth in the aging female brain
Brand: pnas.org
SKU: pnas-org-4
Availability: OnlineOnly

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Persistent metabolic youth in the aging female brain

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Edited by Peter L. Strick, University of Pittsburgh, Pittsburgh, PA, and approved December 21, 2018 (received for review September 14, 2018)Prior work has identified many sex differences in the brain, including during brain aging and in neurodegenerative diseases. Notably, many of these studies are performed by comparing age-matched females and males. Evolutionary theorists have predicted that females might have more youthful brains (neoteny) as compared with males, but until now findings in support of this theory have been limited to postmortem transcriptional analysis, some of which is...

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